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Cell Based Tech Weekly – Pre-Order Multus Media Proliferum M, Mosa Meat Gets $5.7M from Bell Foods Group, Berkeley Lights IPO Soars

Multus Media, a London based company focused on developing cell culture media and growth factors for cell based meat production is launching a pilot scale…

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Multus Media, a London based company focused on developing cell culture media and growth factors for cell based meat production is launching a pilot scale product: Proliferum M — currently available for pre-order

The company, which is currently part of the IndieBio Accelerator is at its core a protein engineering company, engineering high value proteins to efficiently culture mammalian stem cells. 

I spoke with Multus Media CEO and Co-Founder, Cai Linton about the launch of Proliferum M:

  • Proliferum M is a serum replacement meant to be added as a supplement to a basal medium which would contain additional amino acids and nutrients. The current estimated price for the Proliferum M is $100/L → Multus Media has a long term goal to achieve $1/L price point

Multus Media Process:

  1. Protein engineering: Identifying growth factors and proportions for optimal proliferation and differentiation 
  2. Yeast Expression System: developing an engineered yeast strain to produce growth factors 
  3. Achieving Universality: serum replacements that can be used across many cell types

IntegriCulture’s 2nd CulNet Collab

IntegriCulture has another CulNet collaboration in place (following NH Foods): Shiok Meats, Singapore based cell based meat company. https://cellbased.link/culshiok 

  • Through the partnership, Shiok Meats will use Integriculture’s CulNet system and cell based media (SpaceSalt) to scale production of cell based shrimp.
  • Why We Care: This is one of the first collaborations we have seen between two cell based meat companies → Shiok Meats providing cell line and tissue engineering expertise and Integriculture providing cell culture media and proliferation expertise — This may point to the importance of collaboration and democratization of technology rather than a strictly vertically integrated approach to make cell based meat a reality [or companies merging or buying others to achieve vertical integration].
  • Unit Economics: According to a recent article by South China Morning Post, Shiok Meats cell based shrimp currently costs: US$5,000 / 1kilogram.
    • → Goal to bring that cost down to US$50 / 1kilogram and have a product to market by 2021 (perhaps this will be achievable through collaboration with Integriculture). 

Investments

Swiss meat multinational food processor, Bell Foods Group invested $5.7 Million in Mosa Meat – increasing previous investment of 2.8M USD (2018). The new influx of capital will be used to build a pilot production facility, and advance the development and scaling of Mosa Meat technology with a goal to have a product to market in 2022. 

  • Why We Care: Bell Food Group is a strategic partner for Mosa Meat with expertise in producing and marketing meat products. Additional strategic investors include M Ventures, venture capital arm of Merck and animal nutrition company Nutreco. https://cellbased.link/y7n 

Perfect Day raised an additional $160M as an extension of the company’s 2019 Series C round now totaling $300M. The investment was led by Canada Pension Plan Investment Borad’s investment group Thematic Investing and included previous investors Temasek and Horizon Ventures. https://cellbased.link/234f 

Digital cell biology company, Berkeley Lights (BLI) IPO’d on Friday — 7.4 million shares of common stock had an initial estimated price of $16 to $18 per share (revised to $22). It closed on Friday at $65.45, up almost 200%. 

  • Berkeley Lights technology is essentially a “pre-screening” to characterize cells based on their functionality prior to further research and development. Characterizing cells with accuracy and scale, enables Berkeley Lights to develop the most efficient cellular factories for a desired therapeutic or synthetic biology product. 
  • Addressable Business Segments:
    • $6 billion in antibody therapeutics
    • $15 billion in cell therapy
    • $2 billion in synthetic biology
  • Berkeley Lights currently has collaboration agreements in place with Ginkgo Bioworks and Amyris

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